封锁
免疫系统
免疫检查点
癌症研究
医学
脑干
脑瘤
免疫疗法
免疫学
神经科学
生物
病理
内科学
受体
作者
Juyeun Lee,Justin D. Lathia
出处
期刊:Cancer Cell
[Elsevier]
日期:2023-11-01
卷期号:41 (11): 1843-1845
被引量:1
标识
DOI:10.1016/j.ccell.2023.09.016
摘要
Diffuse midline gliomas (DMGs) pose treatment challenges due to their location within the brainstem and invasive nature. Although classical immune checkpoint inhibitors have demonstrated limited success in clinical trials, Ausejo-Mauleon et al. demonstrate TIM-3 is an effective DMG strategy, targeting both immune and tumor cells for dual therapeutic benefit.
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