医学
术后认知功能障碍
发病机制
小RNA
生物信息学
认知
氧化应激
神经科学
联想(心理学)
精神科
基因
免疫学
内科学
生物
遗传学
哲学
认识论
作者
Yuanping Zhong,Yu Zhang,Zhijun Zhu
出处
期刊:Minerva Anestesiologica
[Edizioni Minerva Medica]
日期:2024-03-01
卷期号:90 (3)
被引量:1
标识
DOI:10.23736/s0375-9393.23.17614-0
摘要
Postoperative cognitive dysfunction (POCD) is a significant complication following surgery. The precise mechanisms underlying POCD remain elusive, although it is speculated that they involve central nervous system inflammation, oxidative stress and cellular apoptosis. MicroRNAs (miRNAs), a class of non-coding RNAs widely distributed in eukaryotes, have been implicated in the pathogenesis of neurodegenerative disorders and could potentially impact POCD. This review explores the association between miRNAs and POCD and provides an overview of the progress of current research on miRNAs in the pathogenesis, diagnosis, and treatment of POCD.
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