Kaempferol inhibits atherosclerotic plaque development via dual-targeting of p53-p21-p16 senescence pathway and Nrf2/HO-1/NQO1 antioxidant mechanism: Insights from combined in vivo and in vitro research

Kaempferol significantly ameliorates experimental atherosclerosis via simultaneous antioxidative and anti-senescent actions, highlighting its potential as a therapeutic agent for vascular disease.