结直肠癌
恶性肿瘤
癌症
医学
癌症研究
第1周
肿瘤科
激酶
内科学
生物
细胞周期
遗传学
细胞周期蛋白依赖激酶1
作者
Mai Ly Thi Nguyen,Chi Pham,Tai Suc Nguyen,Phuong Linh Thi Nham,Quynh Chi,Phuong Linh Tran,Anh Vu Nguyen,Nhu Ngoc Nguyen,Dieu Linh Le,Anh Tho Thi Tran,Thi Lap Nguyen,Przemyslaw Bozko,Nguyễn Lĩnh Toàn,Khắc Cường Bùi
标识
DOI:10.21873/anticanres.17319
摘要
Adavosertib effectively inhibits the TP53-wildtype HCT116 cells via the abrogation of intra-S phase cell cycle arrest. Our findings suggest that adavosertib monotherapy may be a potential targeted therapy for CRC.
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