氰化
化学
芳基
催化作用
有机化学
组合化学
药物化学
烷基
作者
Palani Theerthagiri,Appaswami Lalitha
标识
DOI:10.1016/j.tetlet.2012.08.021
摘要
Abstract This work demonstrates an efficient method to prepare α-aryl nitriles by direct cyanation of benzylic alcohol with TMSCN in the presence of a catalytic amount of Zn(OTf) 2 under heating condition. A variety of benzylic alcohols can be converted into the corresponding α-aryl nitriles in good to excellent yields.
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