The results of large scale transcriptional analyses in recent years suggest that sequences in the noncoding parts of the genome may be expressed in the form of noncoding RNAs. And accumulating evidence suggest that noncoding RNA,from 21-24 nt microRNA in length to the length of knt magnitude Xist,has important biological function. This paper mainly expresses some reflection on the future research direction and focus of the non-coding RNA study.