The anti-inflammatory activity of palmitoleic acid from macadamia nuts

expression. Molecular docking analysis suggested that the interaction between POA and NRF2 may involve key residues including valine (VAL-418, VAL-512 and VAL-465). Overall, POA alleviated cell inflammation through the NRF2/TBK1 signaling pathway. This study provides insights into the anti-inflammatory mechanisms of POA, highlighting its potential as a therapeutic agent.