医学
血管紧张素受体阻滞剂
重症监护医学
模式
人口
药物治疗
钙通道
抵抗性高血压
内科学
药理学
血管紧张素转换酶
血压
钙
社会科学
环境卫生
社会学
作者
Mehmet Kanbay,Sidar Çöpür,Cem Tanrıöver,Duygu Uçku,Luke J. Laffin
标识
DOI:10.1016/j.ejim.2023.06.008
摘要
The prevalence of arterial hypertension is approximately 47% in the United States and 55% in Europe. Multiple different medical therapies are used to treat hypertension including diuretics, beta blockers, calcium channel blockers, angiotensin receptor blockers, angiotensin converting enzyme inhibitors, alpha blockers, central acting alpha receptor agonists, neprilysin inhibitors and vasodilators. However, despite the numerous number of medications, the prevalence of hypertension is on the rise, a considerable proportion of the hypertensive population is resistant to these therapeutic modalities and a definitive cure is not possible with the current treatment approaches. Therefore, there is a need for novel therapeutic strategies to provide better treatment and control of hypertension. In this review, our aim is to describe the latest developments in the treatment of hypertension including novel medication classes, gene therapies and RNA-based modalities.
科研通智能强力驱动
Strongly Powered by AbleSci AI