Mechanistic study on enantiodivergent kinetic resolution of axial chiral binaphthol via peptide-phosphonium salt-catalyzed Atherton-Todd reaction

Density functional theory calculations were conducted to elucidate the mechanism and stereoselectivity of Atherton-Todd reaction-guided enantiodivergent kinetic resolution of axial chiral binaphthol catalyzed by peptide-phosphonium salts. The reaction involved the...