Sensing brain plasticity after stroke using magnetic resonance elastography

Stroke is the leading cause of death globally. The infarcted area undergoes a deprivation of oxygen and energy, followed by multiple transient events and reorganization processes called ischemic cascade. MRI is the reference tool for accurate diagnosis, volumetric assessments and age determination of the lesion. The aim of the present study was to investigate the time course of changes in tissue biomechanics after an ischemic event in mice using MRE and study the relationship between stroke volume and tissue biomechanics, to explore a potential role of MRE in assessing the post stroke recovery.