Objective To explore the characteristics of adverse drug reaction in clinic and emergency,to decrease the number of adverse drug reaction.To promoting the reasonable administration.Method CollectED 117 cases of drug adverse reaction from Oct 2008 to Dec 2009 and analyzed the conditions.Results The common conditions were skin allergies and digestive symptoms of ADR,and anti-infectives account at most,nearly about 60%,the second reactions were neurological symptoms and cardiovascular symptoms.Conclusion According to analysis of adverse drug reaction in clinic and emergency,We should get experience of using drugs,and ensure the drugs are in right way.