Electrophoretic techniques in the analysis ofpolydeoxycytidylic acids

Electrophoretic techniques such as capillary zone electrophoresis and one-dimensional polyacrylamide gel electrophoresis were applied in the separation of polydeoxycytidylic acids between 3 and 18 nucleotides in chain length (dC3-dC18). In capillary zone electrophoresis (CZE), the electrophoretic behavior of homo-oligonucleotides in hydrophilic coated capillary (CEP) and polyethyleneimine coated capillary (PEI) was followed under various experimental conditions. One-dimensional polyacrylamide gel electrophoresis was chosen as a supplemental method in the characterization of electrophoretic properties of polydeoxycytidylic acids.