Multiple myeloma; that constitutes 10% of all hematologic malignancies and approximately 1% of whole cancers, is a plasma cell dyscrasia. Extramedullary involvement is often seen in the upper skeletal system, besides it can be seen on the skin and breast, rarely. Extramedullary involvement is generally limited to a single organ. In this article, we present a 70-year-old woman with recurrent skin and breast involvement after multiple treatment with MM diagnosis.