Progress of ketogenic diet in cancer treatment

Recently, more and more studies have indicated that the ketogenic diet began to be used for neurological conditions other than epilepsy.Because of mitochondrial defectiong, tumor cells are unable to use ketone bodies as a primary energy source.The ketogenic diet exerts anti-tumor effect by increasing oxidatetivesress and inhibiting the signal transduction.Besides, ketogenic diet may also enhance the anti-tumor effect of radiation therapy and chemotherapies.The ketogenic diets in tumor models and clinical trials have shown therapeutic effect. Key words: Ketogenic Diet; Cancer; Mechanisms