Objective To explore the efficacy of salvia miltionrrhiza injection combined with MSC in the treatment of cerebral infarction.Methods A total of 30 patients with acute cerebral infarction were randomly divided into the treatment group and the control group.The control group was treated by salvia miltiorrhiza injection;the treatment group was treated with salvia miltionrrhiza injection combined with MSC.Results There was a statistically significant difference at 14 or 28 days after treatment and before in the treatment group(P0.01),and between the treatment group and the control group(P0.05).Conclusion The salvia miltionrrhiza injection combined with MSC in the treatment of cerebral infarction is both safe and practicable.