The problem of signal integrity arises in the result of the signal reflection and crosstalk in the design of High Speed System.MMSP2 is a chip of high performance in the process of video.The design method of High Speed System must be adopted in the design of system based on MMSP2,in order to reduce the problem of signal integrity(reflection,crosstalk,etc.) as possible.HyperLynx is a powerful simulation tool in signal integrity of high speed circuit.The potential problem of signal integrity can be resolved by the simulation of signal integrity with HyperLynx before the manufacture of Printed Circuit Board.