A land utilization and land surface characteristics based urban non-point source pollution prediction model was developed and presented by analysis of urban non-point source pollution source and pollution characteristics. Prediction and simulation on urban rainfall runoff and pollution loads transfer was studied. The model was applied to Hanyang District, Wuhan to study urban non-point source pollution control technology, and satisfactory results were achieved. This model can provide scientific methods for urban water environment programming and non-point source pollution control and management.