Increased expression of CXCR 3 and its ligands in patients with vitiligo and CXCL 10 as a potential clinical marker for vitiligo

The CXCL10/CXCR3 axis mediates T-cell recruitment into the skin in progressive vitiligo. Blocking this chemotactic mechanism may present a new form of therapy. Serum CXCL10 may be a novel biomarker in monitoring disease activity and guiding treatment of progressive vitiligo.