微生物群
先天免疫系统
生物
免疫
寄主(生物学)
造血
免疫系统
免疫学
获得性免疫系统
肠道微生物群
生态学
细胞生物学
遗传学
干细胞
作者
Christoph A. Thaiss,Niv Zmora,Maayan Levy,Eran Elinav
出处
期刊:Nature
[Springer Nature]
日期:2016-07-06
卷期号:535 (7610): 65-74
被引量:1432
摘要
The intestinal microbiome is a signalling hub that integrates environmental inputs, such as diet, with genetic and immune signals to affect the host's metabolism, immunity and response to infection. The haematopoietic and non-haematopoietic cells of the innate immune system are located strategically at the host-microbiome interface. These cells have the ability to sense microorganisms or their metabolic products and to translate the signals into host physiological responses and the regulation of microbial ecology. Aberrations in the communication between the innate immune system and the gut microbiota might contribute to complex diseases.
科研通智能强力驱动
Strongly Powered by AbleSci AI