摘要
Periodontology 2000Volume 42, Issue 1 p. 47-79 Bacterial interactions and successions during plaque development Paul E. Kolenbrander, Paul E. KolenbranderSearch for more papers by this authorRobert J. Palmer Jr, Robert J. Palmer JrSearch for more papers by this authorAlexander H. Rickard, Alexander H. RickardSearch for more papers by this authorNicholas S. Jakubovics, Nicholas S. JakubovicsSearch for more papers by this authorNatalia I. Chalmers, Natalia I. ChalmersSearch for more papers by this authorPatricia I. Diaz, Patricia I. DiazSearch for more papers by this author Paul E. Kolenbrander, Paul E. KolenbranderSearch for more papers by this authorRobert J. Palmer Jr, Robert J. Palmer JrSearch for more papers by this authorAlexander H. Rickard, Alexander H. RickardSearch for more papers by this authorNicholas S. Jakubovics, Nicholas S. JakubovicsSearch for more papers by this authorNatalia I. Chalmers, Natalia I. ChalmersSearch for more papers by this authorPatricia I. Diaz, Patricia I. DiazSearch for more papers by this author First published: 23 August 2006 https://doi.org/10.1111/j.1600-0757.2006.00187.xCitations: 486Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References 1 Aas JA, Paster BJ, Stokes LN, Olsen I, Dewhirst FE. Defining the normal bacterial flora of the oral cavity. J Clin Microbiol 2005: 43: 5721–5732. 2 Amano A, Tamagawa H, Shizukuishi S, Tsunemitsu A. Superoxide dismutase, catalase and peroxidases in oral anaerobic bacteria. J Osaka Univ Dent Sch 1986: 26: 187–192. 3 Bassler BL, Greenberg EP, Stevens AM. Cross-species induction of luminescence in the quorum-sensing bacterium Vibrio harveyi. J Bacteriol 1997: 179: 4043–4045. 4 Blehert DS, Palmer RJ Jr, Xavier JB, Almeida JS, Kolenbrander PE. Autoinducer 2 production by Streptococcus gordonii DL1 and the biofilm phenotype of a luxS mutant are influenced by nutritional conditions. J Bacteriol 2003: 185: 4851–4860. 5 Bourgeau G, McBride BC. Dextran-mediated interbacterial aggregation between dextran-synthesizing streptococci and Actinomycesviscosus. Infect Immun 1976: 13: 1228–1234. 6 Bradshaw DJ, Marsh PD, Allison C, Schilling KM. Effect of oxygen, inoculum composition and flow rate on development of mixed-culture oral biofilms. Microbiology 1996: 142: 623–629. 7 Bradshaw DJ, Marsh PD, Watson GK, Allison C. Role of Fusobacterium nucleatum and coaggregation in anaerobe survival in planktonic and biofilm oral microbial communities during aeration. Infect Immun 1998: 66: 4729–4732. 8 Burgess NA, Kirke DF, Williams P, Winzer K, Hardie KR, Meyers NL, Aduse-Opoku J, Curtis MA, Camara M. LuxS-dependent quorum sensing in Porphyromonas gingivalis modulates protease and haemagglutinin activities but is not essential for virulence. Microbiology 2002: 148: 763–772. 9 Caldwell CE, Marquis RE. Oxygen metabolism by Treponema denticola. Oral Microbiol Immunol 1999: 14: 66–72. 10 Chung WO, Park Y, Lamont RJ, McNab R, Barbieri B, Demuth DR. Signaling system in Porphyromonas gingivalis based on a LuxS protein. J Bacteriol 2001: 183: 3903–3909. 11 Cisar JO, Sandberg AL, Abeygunawardana C, Reddy GP, Bush CA. Lectin recognition of host-like saccharide motifs in streptococcal cell wall polysaccharides. Glycobiology 1995: 5: 655–662. 12 Cisar JO, Sandberg AL, Reddy GP, Abeygunawardana C, Bush CA. Structural and antigenic types of cell wall polysaccharides from viridans group streptococci with receptors for oral actinomyces and streptococcal lectins. Infect Immun 1997: 65: 5035–5041. 13 Delisle AL, Donkersloot JA, Kolenbrander PE, Tylenda CA. Use of lytic bacteriophage for Actinomyces viscosus T14V as a probe for cell surface components mediating intergeneric coaggregation. Infect Immun 1988: 56: 54–59. 14 Demuth DR, Duan Y, Brooks W, Holmes AR, McNab R, Jenkinson HF. Tandem genes encode cell-surface polypeptides SspA and SspB which mediate adhesion of the oral bacterium Streptococcus gordonii to human and bacterial receptors. Mol Microbiol 1996: 20: 403–413. 15 Diaz PI, Zilm PS, Rogers AH. The response to oxidative stress of Fusobacterium nucleatum grown in continuous culture. FEMS Microbiol Lett 2000: 187: 31–34. 16 Diaz PI, Zilm PS, Rogers AH. Fusobacterium nucleatum supports the growth of Porphyromonas gingivalis in oxygenated and carbon-dioxide-depleted environments. Microbiology 2002: 148: 467–472. 17 Diaz PI, Slakeski N, Reynolds EC, Morona R, Rogers AH, Kolenbrander PE. Role of oxyR in the oral anaerobe Porphyromonas gingivalis. J Bacteriol 2006: 188: 2454–2462. 18 Diaz PI, Chalmers NI, Rickard AH, Kong C, Milburn CL, Palmer RJ Jr, Kolenbrander PE. Molecular characterization of subject-specific oral microflora during initial colonization of enamel. Appl Environ Microbiol 2006: 72: 2837–2842. 19 Diehl SR, Wang Y, Brooks CN, Burmeister JA, Califano JV, Wang S, Schenkein HA. Linkage disequilibrium of interleukin-1 genetic polymorphisms with early-onset periodontitis. J Periodontol 1999: 70: 418–430. 20 DiRienzo JM, Porter-Kaufman J, Haller J, Rosan B. Corncob formation: a morphological model for molecular studies of bacterial interactions. In: SE Mergenhagen, B Rosan, editors. Molecular Basis of Oral Microbial Adhesion. Washington, DC: American Society for Microbiology, 1995: 172–176. 21 Duerre JA, Baker DJ, Salisbury L. Structure elucidation of a carbohydrate derived from S-ribosylhomocysteine by enzymatic cleavage. Fed Proc 1971: 30: 1067. 22 Ebisu S, Nakae H, Okada H. Coaggregation of Eikenella corrodens with oral bacteria mediated by bacterial lectin-like substance. Adv Dent Res 1988: 2: 323–327. 23 Eckburg PB, Bik EM, Bernstein CN, Purdom E, Dethlefsen L, Sargent M, Gill SR, Nelson KE, Relman DA. Diversity of the human intestinal microbial flora. Science 2005: 308: 1635–1638. 24 Egland PG, Dû LD, Kolenbrander PE. Identification of independent Streptococcus gordonii SspA and SspB functions in coaggregation with Actinomyces naeslundii. Infect Immun 2001: 69: 7512–7516. 25 Egland PG, Palmer RJ Jr, Kolenbrander PE. Interspecies communication in Streptococcus gordonii-Veillonella atypica biofilms: signaling in flow conditions requires juxtaposition. Proc Natl Acad Sci U S A 2004: 101: 16917–16922. 26 Federle MJ, Bassler BL. Interspecies communication in bacteria. J Clin Invest 2003: 112: 1291–1299. 27 Fong KP, Chung WO, Lamont RJ, Demuth DR. Intra- and interspecies regulation of gene expression by Actinobacillus actinomycetemcomitans LuxS. Infect Immun 2001: 69: 7625–7634. 28 Foster JS, Kolenbrander PE. Development of a multispecies oral bacterial community in a saliva-conditioned flow cell. Appl Environ Microbiol 2004: 70: 4340–4348. 29 Frias J, Olle E, Alsina M. Periodontal pathogens produce quorum sensing signal molecules. Infect Immun 2001: 69: 3431–3434. 30 Fuqua WC, Winans SC, Greenberg EP. Quorum sensing in bacteria: the LuxR-LuxI family of cell density-responsive transcriptional regulators. J Bacteriol 1994: 176: 269–275. 31 Gibbons RJ, Nygaard M. Interbacterial aggregation of plaque bacteria. Arch Oral Biol 1970: 15: 1397–1400. 32 Hellstrom MK, Ramberg P, Krok L, Lindhe J. The effect of supragingival plaque control on the subgingival microflora in human periodontitis. J Clin Periodontol 1996: 23: 934–940. 33 Higuchi M. Reduced nicotinamide adenine dinucleotide oxidase involvement in defense against oxygen toxicity of Streptococcus mutans. Oral Microbiol Immunol 1992: 7: 309–314. 34 Hosogi Y, Duncan MJ. Gene expression in Porphyromonas gingivalis after contact with human epithelial cells. Infect Immun 2005: 73: 2327–2335. 35 Hsu SD, Cisar JO, Sandberg AL, Kilian M. Adhesive properties of viridans streptococcal species. Microb Ecol Health Dis 1994: 7: 125–137. 36 Hughes CV, Kolenbrander PE, Andersen RN, Moore LV. Coaggregation properties of human oral Veillonella spp.: relationship to colonization site and oral ecology. Appl Environ Microbiol 1988: 54: 1957–1963. 37 Hughes CV, Andersen RN, Kolenbrander PE. Characterization of Veillonella atypica PK1910 adhesin-mediated coaggregation with oral Streptococcus spp. Infect Immun 1992: 60: 1178–1186. 38 Hunt SM, Werner EM, Huang B, Hamilton MA, Stewart PS. Hypothesis for the role of nutrient starvation in biofilm detachment. Appl Environ Microbiol 2004: 70: 7418–7425. 39 Imlay JA. How oxygen damages microbes: oxygen tolerance and obligate anaerobiosis. Adv Microb Physiol 2002: 46: 111–153. 40 Jones SJ. A special relationship between spherical and filamentous microorganisms in mature human dental plaque. Arch Oral Biol 1972: 17: 613–616. 41 Kaplan JB, Meyenhofer MF, Fine DH. Biofilm growth and detachment of Actinobacillus actinomycetemcomitans. J Bacteriol 2003: 185: 1399–1404. 42 Kaplan JB, Velliyagounder K, Ragunath C, Rohde H, Mack D, Knobloch JK, Ramasubbu N. Genes involved in the synthesis and degradation of matrix polysaccharide in Actinobacillus actinomycetemcomitans and Actinobacillus pleuropneumoniae biofilms. J Bacteriol 2004: 186: 8213–8220. 43 Keller L, Surette MG. Communication in bacteria: an ecological and evolutionary perspective. Nat Rev Microbiol 2006: 4: 249–258. 44 Kigure T, Saito A, Seida K, Yamada S, Ishihara K, Okuda K. Distribution of Porphyromonas gingivalis and Treponema denticola in human subgingival plaque at different periodontal pocket depths examined by immunohistochemical methods. J Periodontal Res 1995: 30: 332–341. 45 Klier CM, Kolenbrander PE, Roble AG, Marco ML, Cross S, Handley PS. Identification of a 95 kDa putative adhesin from Actinomyces serovar WVA963 strain PK1259 that is distinct from type 2 fimbrial subunits. Microbiology 1997: 143: 835–846. 46 Klier CM, Roble AG, Kolenbrander PE. Actinomyces serovar WVA963 coaggregation-defective mutant strain PK2407 secretes lactose-sensitive adhesin that binds to coaggregation partner Streptococcus oralis 34. Oral Microbiol Immunol 1998: 13: 337–340. 47 Kolenbrander PE. Isolation and characterization of coaggregation-defective mutants of Actinomyces viscosus, Actinomyces naeslundii, and Streptococcus sanguis. Infect Immun 1982: 37: 1200–1208. 48 Kolenbrander PE. Intergeneric coaggregation among human oral bacteria and ecology of dental plaque. Annu Rev Microbiol 1988: 42: 627–656. 49 Kolenbrander PE. Surface recognition among oral bacteria: multigeneric coaggregations and their mediators. Crit Rev Microbiol 1989: 17: 137–159. 50 Kolenbrander PE. Coaggregation: adherence in the human oral microbial ecosystem. In: M Dworkin, M Dworkins, editors. Microbial Cell-cell Interactions. Washington, DC: American Society for Microbiology, 1991: 303–329. 51 Kolenbrander PE. Coaggregation of human oral bacteria: potential role in the accretion of dental plaque. J Appl Bacteriol 1993: 74 (Suppl.): 79S–86S. 52 Kolenbrander PE. Oral microbial communities: biofilms, interactions, and genetic systems. Annu Rev Microbiol 2000: 54: 413–437. 53 Kolenbrander PE, Andersen RN. Use of coaggregation-defective mutants to study the relationships of cell-to-cell interactions and oral microbial ecology. In: SE Mergenhagen, B Rosan, editors. Molecular Basis of Oral Microbial Adhesion. Washington, DC: American Society for Microbiology, 1985: 164–171. 54 Kolenbrander PE, Andersen RN. Multigeneric aggregations among oral bacteria: a network of independent cell-to-cell interactions. J Bacteriol 1986: 168: 851–859. 55 Kolenbrander PE, Andersen RN. Characterization of Streptococcus gordonii (S. sanguis) PK488 adhesin- mediated coaggregation with Actinomyces naeslundii PK606. Infect Immun 1990: 58: 3064–3072. 56 Kolenbrander PE, London J. Ecological significance of coaggregation among oral bacteria. Adv Microb Ecol 1992: 12: 183–217. 57 Kolenbrander PE, London J. Adhere today, here tomorrow: oral bacterial adherence. J Bacteriol 1993: 175: 3247–3252. 58 Kolenbrander PE, Andersen RN, Holdeman LV. Coaggregation of oral Bacteroides species with other bacteria: central role in coaggregation bridges and competitions. Infect Immun 1985: 48: 741–746. 59 Kolenbrander PE, Andersen RN, Moore LV. Coaggregation of Fusobacterium nucleatum, Selenomonas flueggei, Selenomonas infelix, Selenomonas noxia, and Selenomonas sputigena with strains from 11 genera of oral bacteria. Infect Immun 1989: 57: 3194–3203. 60 Kolenbrander PE, Andersen RN, Moore LVH. Intrageneric coaggregation among strains of human oral bacteria: potential role in primary colonization of the tooth surface. Appl Environ Microbiol 1990: 56: 3890–3894. 61 Kolenbrander PE, Andersen RN, Blehert DS, Egland PG, Foster JS, Palmer RJ Jr. Communication among oral bacteria. Microbiol Mol Biol Rev 2002: 66: 486–505. 62 Kornman KS, Crane A, Wang HY, Di Giovine FS, Newman MG, Pirk FW, Wilson TG Jr, Higginbottom FL, Duff GW. The interleukin-1 genotype as a severity factor in adult periodontal disease. J Clin Periodontol 1997: 24: 72–77. 63 Kroes I, Lepp PW, Relman DA. Bacterial diversity within the human subgingival crevice. Proc Natl Acad Sci U S A 1999: 96: 14547–14552. 64 Lai CH, Bloomquist C, Liljemark WF. Purification and characterization of an outer membrane protein adhesin from Haemophilus parainfluenzae HP-28. Infect Immun 1990: 58: 3833–3839. 65 Li J, Helmerhorst EJ, Leone CW, Troxler RF, Yaskell T, Haffajee AD, Socransky SS, Oppenheim FG. Identification of early microbial colonizers in human dental biofilm. J Appl Microbiol 2004: 97: 1311–1318. 66 Listgarten MA. Structure of the microbial flora associated with periodontal health and disease in man. A light and electron microscopic study. J Periodontol 1976: 47: 1–18. 67 Listgarten MA, Mayo H, Amsterdam M. Ultrastructure of the attachment device between coccal and filamentous microorganisms in ‘corn cob’ formations of dental plaque. Arch Oral Biol 1973: 18: 651–656. 68 Listgarten MA, Mayo HE, Tremblay R. Development of dental plaque on epoxy resin crowns in man. A light and electron microscopic study. J Periodontol 1975: 46: 10–26. 69 Löe H, Theilade E, Jensen SB. Experimental gingivitis in man. J Periodontol 1965: 36: 177–187. 70 Lynch MC, Kuramitsu HK. Role of superoxide dismutase activity in the physiology of Porphyromonas gingivalis. Infect Immun 1999: 67: 3367–3375. 71 Mager DL, Ximenez-Fyvie LA, Haffajee AD, Socransky SS. Distribution of selected bacterial species on intraoral surfaces. J Clin Periodontol 2003: 30: 644–654. 72 Mashburn LM, Jett AM, Akins DR, Whiteley M. Staphylococcus aureus serves as an iron source for Pseudomonas aeruginosa during in vivo coculture. J Bacteriol 2005: 187: 554–566. 73 McIntire FC, Vatter AE, Baros J, Arnold J. Mechanism of coaggregation between Actinomyces viscosus T14V and Streptococcus sanguis 34. Infect Immun 1978: 21: 978–988. 74 McIntire FC, Crosby LK, Vatter AE. Inhibitors of coaggregation between Actinomyces viscosus T14V and Streptococcus sanguis 34: beta-galactosides, related sugars, and anionic amphipathic compounds. Infect Immun 1982: 36: 371–378. 75 McNab R, Ford SK, El-Sabaeny A, Barbieri B, Cook GS, Lamont RJ. LuxS-based signaling in Streptococcus gordonii: autoinducer 2 controls carbohydrate metabolism and biofilm formation with Porphyromonas gingivalis. J Bacteriol 2003: 185: 274–284. 76 Miller ST, Xavier KB, Campagna SR, Taga ME, Semmelhack MF, Bassler BL, Hughson FM. Salmonella typhimurium recognizes a chemically distinct form of the bacterial quorum-sensing signal autoinducer-2. Mol Cell 2004: 15: 677–687. 77 Mizuno J, Cisar JO, Vatter AE, Fennessey PV, McIntire FC. A factor from Actinomyces viscosus T14V that specifically aggregates Streptococcus sanguis H1. Infect Immun 1983: 40: 1204–1213. 78 Moore WEC, Moore LVH. The bacteria of periodontal diseases. Periodontol 2000 1994: 5: 66–77. 79 Moore WE, Holdeman LV, Smibert RM, Hash DE, Burmeister JA, Ranney RR. Bacteriology of severe periodontitis in young adult humans. Infect Immun 1982: 38: 1137–1148. 80 Moore WE, Holdeman LV, Cato EP, Smibert RM, Burmeister JA, Ranney RR. Bacteriology of moderate (chronic) periodontitis in mature adult humans. Infect Immun 1983: 42: 510–515. 81 Mouton C, Reynolds HS, Gasiecki EA, Genco RJ. Combined micromanipulation, culture and immunofluorescent techniques for the isolation of the coccal organisms comprising the ‘corn-cob’ configuration of human dental plaque. J Biol Buccale 1979: 5: 321–332. 82 Noiri Y, Ebisu S. Identification of periodontal disease-associated bacteria in the ‘‘plaque-free zone’’. J Periodontol 2000: 71: 1319–1326. 83 Noiri Y, Ozaki K, Nakae H, Matsuo T, Ebisu S. An immunohistochemical study on the localization of Porphyromonas gingivalis, Campylobacter rectus and Actinomyces viscosus in human periodontal pockets. J Periodontal Res 1997: 32: 598–607. 84 Noiri Y, Li L, Ebisu S. The localization of periodontal-disease-associated bacteria in human periodontal pockets. J Dent Res 2001: 80: 1930–1934. 85 Noiri Y, Li L, Yoshimura F, Ebisu S. Localization of Porphyromonas gingivalis-carrying fimbriae in situ in human periodontal pockets. J Dent Res 2004: 83: 941–945. 86 Nyvad B, Fejerskov O. Scanning electron microscopy of early microbial colonization of human enamel and root surfaces in vivo. Scand J Dent Res 1987: 95: 287–296. 87 Nyvad B, Kilian M. Microbiology of the early colonization of human enamel and root surfaces in vivo. Scand J Dent Res 1987: 95: 369–380. 88 Nyvad B, Kilian M. Comparison of the initial streptococcal microflora on dental enamel in caries-active and in caries-inactive individuals. Caries Res 1990: 24: 267–272. 89 Palmer RJ Jr, Caldwell DE. A flowcell for the study of plaque removal and regrowth. J Microbiol Methods 1995: 24: 171–182. 90 Palmer RJ Jr, Kazmerzak K, Hansen MC, Kolenbrander PE. Mutualism vs. independence: strategies of mixed-species oral biofilms in vitro using saliva as the sole nutrient source. Infect Immun 2001: 69: 5794–5804. 91 Palmer RJ Jr, Wu R, Gordon S, Bloomquist CG, Liljemark WF, Kilian M, Kolenbrander PE. Retrieval of biofilms from the oral cavity. Methods Enzymol 2001: 337: 393–403. 92 Palmer RJ Jr, Gordon SM, Cisar JO, Kolenbrander PE. Coaggregation-mediated interactions of streptococci and actinomyces detected in initial human dental plaque. J Bacteriol 2003: 185: 3400–3409. 93 Paster BJ, Boches SK, Galvin JL, Ericson RE, Lau CN, Levanos VA, Sahasrabudhe A, Dewhirst FE. Bacterial diversity in human subgingival plaque. J Bacteriol 2001: 183: 3770–3783. 94 Quirynen M, Vogels R, Pauwels M, Haffajee AD, Socransky SS, Uzel NG, Van Steenberghe D. Initial subgingival colonization of ‘pristine’ pockets. J Dent Res 2005: 84: 340–344. 95 Ramasubbu N, Thomas LM, Ragunath C, Kaplan JB. Structural analysis of dispersin B, a biofilm-releasing glycoside hydrolase from the periodontopathogen Actinobacillus actinomycetemcomitans. J Mol Biol 2005: 349: 475–486. 96 Ramberg P, Sekino S, Uzel NG, Socransky S, Lindhe J. Bacterial colonization during de novo plaque formation. J Clin Periodontol 2003: 30: 990–995. 97 Rickard AH, Palmer RJ Jr, Blehert DS, Campagna SR, Semmelhack MF, Egland PG, Bassler BL, Kolenbrander PE. Autoinducer 2: a concentration-dependent signal for mutualistic biofilm growth. Mol Microbiol 2006: 60: 1446–1456. 98 Ritz HL. Microbial population shifts in developing human dental plaque. Arch Oral Biol 1967: 12: 1561–1568. 99 Schauder S, Shokat K, Surette MG, Bassler BL. The LuxS family of bacterial autoinducers: biosynthesis of a novel quorum-sensing signal molecule. Mol Microbiol 2001: 41: 463–476. 100 Semmelhack MF, Campagna SR, Federle MJ, Bassler BL. An expeditious synthesis of DPD and boron binding studies. Org Lett 2005: 7: 569–572. 101 Socransky SS, Haffajee AD. Periodontal microbial ecology. Periodontol 2000 2005: 38: 135–187. 102 Socransky SS, Manganiello AD, Propas D, Oram V, Van Houte J. Bacteriological studies of developing supragingival dental plaque. J Periodontal Res 1977: 12: 90–106. 103 Socransky SS, Smith C, Martin L, Paster BJ, Dewhirst FE, Levin AE. Checkerboard DNA-DNA hybridization. Biotechniques 1994: 17: 788–792. 104 Socransky SS, Haffajee AD, Cugini MA, Smith C, Kent RL Jr. Microbial complexes in subgingival plaque. J Clin Periodontol 1998: 25: 134–144. 105 Stanton TB, Jensen NS. Purification and characterization of NADH oxidase from Serpulina (Treponema) hyodysenteriae. J Bacteriol 1993: 175: 2980–2987. 106 Storz G, Zheng M. Oxidative stress. In: G Storz, R Hengge-Aronis, editors. Bacterial Stress Responses. Washington, DC: ASM Press, 2000: 47–59. 107 Sunde PT, Olsen I, Gobel UB, Theegarten D, Winter S, Debelian GJ, Tronstad L, Moter A. Fluorescence in situ hybridization (FISH) for direct visualization of bacteria in periapical lesions of asymptomatic root-filled teeth. Microbiology 2003: 149: 1095–1102. 108 Surette MG, Bassler BL. Quorum sensing in Escherichia coli and Salmonella typhimurium. Proc Natl Acad Sci U S A 1998: 95: 7046–7050. 109 Sztukowska M, Bugno M, Potempa J, Travis J, Kurtz DM. Role of rubrerythrin in the oxidative stress response of Porphyromonas gingivalis. Mol Microbiol 2002: 44: 479–488. 110 Tanner A, Maiden MF, Macuch PJ, Murray LL, Kent RL Jr. Microbiota of health, gingivitis, and initial periodontitis. J Clin Periodontol 1998: 25: 85–98. 111 Theilade E, Theilade J. Formation and ecology of plaque at different locations in the mouth. Scand J Dent Res 1985: 93: 90–95. 112 Theilade E, Wright WH, Jensen SB, Löe H. Experimental gingivitis in man. II. A longitudinal clinical and bacteriological investigation. J Periodontal Res 1966: 1: 1–13. 113 Tinanoff N, Gross A, Brady JM. Development of plaque on enamel: parallel investigations. J Periodontal Res 1976: 11: 197–209. 114 Wecke J, Kersten T, Madela K, Moter A, Göbel UB, Friedmann A, Bernimoulin JP. A novel technique for monitoring the development of bacterial biofilms in human periodontal pockets. FEMS Microbiol Lett 2000: 191: 95–101. 115 Weiss EI, Kolenbrander PE, London J, Hand AR, Andersen RN. Fimbria-associated proteins of Bacteroides loescheii PK1295 mediate intergeneric coaggregations. J Bacteriol 1987: 169: 4215–4222. 116 Weiss EI, London J, Kolenbrander PE, Andersen RN, Fischler C, Siraganian RP. Characterization of monoclonal antibodies to fimbria-associated adhesins of Bacteroides loescheii PK1295. Infect Immun 1988: 56: 219–224. 117 Whittaker CJ, Klier CM, Kolenbrander PE. Mechanisms of adhesion by oral bacteria. Annu Rev Microbiol 1996: 50: 513–552. 118 Ximenez-Fyvie LA, Haffajee AD, Socransky SS. Microbial composition of supra- and subgingival plaque in subjects with adult periodontitis. J Clin Periodontol 2000: 27: 722–732. 119 Ximenez-Fyvie LA, Haffajee AD, Socransky SS. Comparison of the microbiota of supra- and subgingival plaque in health and periodontitis. J Clin Periodontol 2000: 27: 648–657. 120 Yumoto H, Azakami H, Nakae H, Matsuo T, Ebisu S. Cloning, sequencing and expression of an Eikenella corrodens gene encoding a component protein of the lectin-like adhesin complex. Gene 1996: 183: 115–121. 121 Zheng M, Wang X, Doan B, Lewis KA, Schneider TD, Storz G. Computation-directed identification of OxyR DNA binding sites in Escherichia coli. J Bacteriol 2001: 183: 4571–4579. Citing Literature Volume42, Issue1October 2006Pages 47-79 ReferencesRelatedInformation