粒体自噬
医学
肺
羟考酮
药理学
内科学
自噬
化学
细胞凋亡
生物化学
受体
类阿片
作者
Cuicui Liu,Yanting Wang,Shaona Li,Jia Shi,Pei Wang,Ma Yang,Xiangkun Li,Jianbo Yu
出处
期刊：Clinics
[Fundacao Faculdade de Medicina]
日期：2025-01-01
卷期号：80: 100753-100753
标识
DOI：10.1016/j.clinsp.2025.100753
摘要
HO-1 deficiency partially counteracts the beneficial effects of oxycodone on pulmonary protection and inhibition of mitophagy both in vivo and in vitro. Oxycodone pretreatment attenuated LPS-induced systemic inflammation and subsequent lung injury by regulating mitophagy via the HO-1 pathway.
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