Advancements in Asymmetric Catalytic Approaches Involving Benzoxazinone Derivatives

Abstract Chiral aza ‐heterocycles, as a sort of key frameworks of natural products et al , are deeply concerned by synthetic chemists. In recent years, catalytic asymmetric reactions of several types of zwitterionic intermediates, originating form benzoxazinone derivatives, have become a popular and efficient approach to obtain chiral aza ‐heterocycles. Given that, this review attempts to summarize recent development in the field of catalytic asymmetric reactions of benzoxazinone derivatives as a powerful dipole precursors for the construction of aza ‐heterocycles. In the past years, various benzoxazinone derivatives and their catalytic asymmetric reactions have been developed. Herein, this review is organized by the types of benzoxazinone derivatives and their catalytic asymmetric reactions to display their important synthetic potentials and values.