清晨好,您是今天最早来到科研通的研友!由于当前在线用户较少,发布求助请尽量完整的填写文献信息,科研通机器人24小时在线,伴您科研之路漫漫前行!

Sex differences in the prevalence and correlates of suicide attempts in patients with first-episode and drug-naïve psychotic major depression

哈姆德 萧条(经济学) 内科学 焦虑 血压 医学 入射(几何) 心理学 自杀未遂 精神科 临床心理学 毒物控制 伤害预防 经济 宏观经济学 物理 环境卫生 光学
作者
Weijian Liu,Chunyu Yang,Xiangyang Zhang
出处
期刊:Psychopathology [Karger Publishers]
卷期号:: 1-21
标识
DOI:10.1159/000542844
摘要

Purpose: Sex differences play an important role in depression prevalence, symptom profile, treatment response, and disease course. However, sex differences in factors associated with suicide attempts (SAs) in first-episode and drug-naïve (FEDN) patients with psychotic major depression (PMD) remain unclear. Methods: In this study, 171 patients with FEDN PMD were recruited. Patients’ symptoms were assessed using the Hamilton Depression Scale (HAMD), Hamilton Anxiety Scale (HAMA), and Positive and Negative Syndrome Scale (PANSS) positive subscale. In addition, metabolic parameters and thyroid hormone levels were measured. Results: The prevalence of SA was remarkably high in both male and female PMD patients (53.19% vs. 50.81%), without significant differences between the two groups. In male PMD patients, the combination of marital status and TSH levels was found to effectively distinguish between SA and non-SA cases, with an AUC value of 0.87. In addition, the HAMD score and diastolic blood pressure (BP) were significantly associated with the frequency of SAs in this subgroup. For female PMD patients, the combination of positive score, diastolic BP, TSH, and TgAb was found to be a very effective discriminator between SA and non-SA cases, with an AUC of 0.91. Furthermore, duration of illness, positive score, systolic BP, and TPOAb were found to be significantly associated with the frequency of SAs in this subgroup. Conclusions: Our results indicate a high incidence of suicide attempts in both men and women with PMD. Several clinically relevant factors, metabolic parameters, and thyroid hormone function contribute to sex differences in suicide attempts in FEDN PMD patients.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
胡可完成签到 ,获得积分10
5秒前
CipherSage应助科研通管家采纳,获得10
8秒前
倩倩完成签到 ,获得积分10
16秒前
manmanzhong完成签到 ,获得积分10
49秒前
52秒前
jason发布了新的文献求助10
55秒前
lucky完成签到 ,获得积分10
55秒前
杪夏二八完成签到 ,获得积分10
1分钟前
乐乐应助XD824采纳,获得10
1分钟前
英姑应助XD824采纳,获得10
1分钟前
小二郎应助XD824采纳,获得10
1分钟前
bc应助XD824采纳,获得50
1分钟前
充电宝应助XD824采纳,获得10
1分钟前
xingsixs完成签到 ,获得积分10
1分钟前
糖炒小米粒完成签到,获得积分20
1分钟前
XD824发布了新的文献求助10
1分钟前
WenJun完成签到,获得积分10
1分钟前
科研通AI2S应助科研通管家采纳,获得10
2分钟前
2分钟前
jason完成签到,获得积分10
2分钟前
Liu_cx发布了新的文献求助10
2分钟前
丹妮完成签到 ,获得积分10
2分钟前
3分钟前
糟糕的翅膀完成签到,获得积分10
3分钟前
001发布了新的文献求助10
3分钟前
wodetaiyangLLL完成签到 ,获得积分10
3分钟前
小西完成签到 ,获得积分10
3分钟前
酸辣完成签到 ,获得积分10
3分钟前
John完成签到 ,获得积分10
4分钟前
沙海沉戈完成签到,获得积分0
4分钟前
4分钟前
muriel完成签到,获得积分10
4分钟前
JY发布了新的文献求助10
4分钟前
naczx完成签到,获得积分0
4分钟前
orixero应助CC采纳,获得10
5分钟前
5分钟前
科研通AI5应助萨尔莫斯采纳,获得10
5分钟前
尧桦发布了新的文献求助10
5分钟前
5分钟前
尧桦完成签到,获得积分10
5分钟前
高分求助中
Les Mantodea de Guyane Insecta, Polyneoptera 2500
Mobilization, center-periphery structures and nation-building 600
Technologies supporting mass customization of apparel: A pilot project 600
Introduction to Strong Mixing Conditions Volumes 1-3 500
Fine Chemicals through Heterogeneous Catalysis 430
China—Art—Modernity: A Critical Introduction to Chinese Visual Expression from the Beginning of the Twentieth Century to the Present Day 430
Multichannel rotary joints-How they work 400
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 物理 生物化学 纳米技术 计算机科学 化学工程 内科学 复合材料 物理化学 电极 遗传学 量子力学 基因 冶金 催化作用
热门帖子
关注 科研通微信公众号,转发送积分 3795590
求助须知:如何正确求助?哪些是违规求助? 3340645
关于积分的说明 10300891
捐赠科研通 3057168
什么是DOI,文献DOI怎么找? 1677522
邀请新用户注册赠送积分活动 805449
科研通“疑难数据库(出版商)”最低求助积分说明 762608