Type 1 diabetes and associated autoimmune diseases

BACKGROUND: Common autoimmune diseases (AID) tend to occur together in the same individual and families. Type 1 diabetes (T1D) is caused by an autoimmune-induced inflammatory destruction of the pancreatic tissue and clusters with several other AID. AIM: those with T1D and associated AID. METHODS: From October 1999 to February 2020, a total of 665 patients with T1D and their first-degree relatives were evaluated. RESULTS: those with T1D only. However, the prevalence of AID and autoantibodies against various tissues were found to be higher in relatives of patients with T1D only compared to relatives of patients with T1D + AID. CONCLUSION: Annual serological and subsequent functional screening for AID in patients with T1D and their first-degree relatives is recommended.