医学
金黄色葡萄球菌
化脓性关节炎
关节炎
内科学
感染性心内膜炎
微生物学
细菌
生物
遗传学
作者
Yongseop Lee,Yun Suk Cho,Yujin Sohn,Jong Hoon Hyun,Sang Min Ahn,Woon Ji Lee,Jung Ho Kim,Hye Seong,Junhyung Kim,Su Jin Jeong,Nam Su Ku,Joon‐Sup Yeom,Jin Young Ahn,Jun Yong Choi
出处
期刊:Infection and Chemotherapy
[Korean Society of Infectious Diseases and Korean Society for Chemotherapy (KAMJE)]
日期:2020-01-01
卷期号:52 (4): 503-503
被引量:7
标识
DOI:10.3947/ic.2020.52.4.503
摘要
Background The aim of this study was to describe the clinical and microbiological characteristics of infective arthritis and to analyze risk factors for Gram-negative bacterial infections that cause infective arthritis. Materials and methods Patients admitted between 2009 - 2018 with infective arthritis in a single-tertiary hospital were evaluated retrospectively. Results A total of 181 patients were enrolled in this study. Of them, 135 were native joint infection patients and 46 were prosthetic joint infection patients. The most common site of infective arthritis was the knee (63.6%), followed by the shoulder (17.7%), and the hip (9.9%). The most frequently identified microorganisms were Staphylococcus aureus (51.1%), followed by Streptococci sp. (21.1%), Enterobacteriaceae (8.4%), and coagulase-negative-Staphylococci (CNS; 8.4%). Infections due to Gram-negative bacteria and fungi made up 13.7% and 3.2% of all cases, respectively. Additionally, 20% and 4.2% of the cases involved methicillin-resistant S. aureus (MRSA) and MRCNS. We found that bacteriuria, infective arthritis in the hip, and steroid use at admission are independent risk factors for Gram-negative bacterial infections. Conclusion Infective arthritis with methicillin-resistant microorganisms reached up to about 25% in a single-tertiary hospital in Korea. In case of suspected urinary tract infection, infective arthritis of the hip joint, or steroid use at admission time among infective arthritis patients, empirical treatment covering Gram-negative microorganisms can be considered.
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