Regenerative Medicine: A Scaffold Therapy in Heart Regeneration Through Tissue Engineering.

Organ and tissue loss through any injury motivate to formulate or develop new techniques that can generate tissues and decrease the dependency of transplantation. Regenerative medicine is an interdisciplinary field that solely depends on the principle of engineering and life science. These techniques used to fabricate cell sheets on biomaterials and then grafted it on host tissues to heal injury. Regenerative medicine involves use of substrate such a bioreactors and growth factors with cells and scaffold, which shows increase in the regenerative capacity of host tissues by using cell injection or immune modulation. Object of the present research is to reprograming of somatic cells to pluripotent cells that holds huge potential of regenerative medicine. Tissues are grafting in 3D construction by different techniques in tissue engineering. Bio-printing is an enabling technology of tissue engineering that promises to fabricate highly mimicked organs with a digital control. It gives the understanding of biomaterials and stem cell biology to integrate various printing mechanism for multi-phase tissue engineering.