小型化                        
                
                                
                        
                            光学                        
                
                                
                        
                            材料科学                        
                
                                
                        
                            折射率                        
                
                                
                        
                            各向同性                        
                
                                
                        
                            相(物质)                        
                
                                
                        
                            宽带                        
                
                                
                        
                            螺旋(铁路)                        
                
                                
                        
                            生物成像                        
                
                                
                        
                            相位对比成像                        
                
                                
                        
                            纳米技术                        
                
                                
                        
                            光电子学                        
                
                                
                        
                            物理                        
                
                                
                        
                            相衬显微术                        
                
                                
                        
                            数学分析                        
                
                                
                        
                            荧光                        
                
                                
                        
                            量子力学                        
                
                                
                        
                            数学                        
                
                        
                    
            作者
            
                Youngjin Kim,Gun‐Yeal Lee,Jangwoon Sung,Junhyeok Jang,Byoungho Lee            
         
                    
        
    
            
            标识
            
                                    DOI:10.1002/adfm.202106050
                                    
                                
                                 
         
        
                
            摘要
            
            Abstract Spiral phase contrast imaging offers an excellent opportunity to observe non‐labeled biological samples with slight variations in refractive index or thickness. However, the overall system covering previous works is still complex and bulky, hindering miniaturization and compatibility with conventional systems. Furthermore, high‐resolution imaging, particularly for observing biological specimens such as cellular structures, requires several refractive optical elements like objectives and relay optics which dramatically increases the system form factor. Here, it is demonstrated that a metalens, in which the phase profile is a sum of the hyperbolic phase and spiral phase with a topological charge of 1, performs 2D isotropic edge‐enhanced imaging. The metalens achieves a submicrometer resolution of up to 0.78 µm operated under visible broadband range in conjunction with a compact form factor. Furthermore, experiments with biological samples can additionally prove the feasibility of practical usage. Capitalizing on compactness and high‐resolution characteristics, it is believed that the scheme provides a stepping stone to biomedical imaging technologies and analog computing.
         
            
 
                 
                
                    
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