Scutellaria baicalensis Georgi and four Chinese herb combinations were combined with five kinds of antimicrobials respectively to determine their inhibitory effects on Escherichia coli.The results showed that different combinations differed greatly in inhibitory effect.Combinations of Scutellaria baicalensis Georgi with the five antimicrobials could significantly inhibit the growth of both standard Escherichia coli and resistant Escherichia coli.In all,most combinations studied had an effect on inhibiting Escherichia coli,and sensitivity of standard Escherichia coli and resistant Escherichia coli were different in the same combination.