Research progress on physicochemical properties， mechanism of action， and application of glucose oxidase in animal production

Glucose oxidase (GOD) is an aerobic dehydrogenase, which widely exists in animals, plants and microorganisms. GOD can catalyze the conversion of glucose into δ-gluconolactone and hydrogen peroxide, which then spontaneously hydrolyzes to produce gluconic acid. GOD has multiple biological functions, on the one hand, it can consume oxygen to create an anaerobic environment, inhibiting the growth of harmful bacteria while promoting the proliferation of beneficial bacteria. On the other hand, the generated gluconic acid can reduce the pH value of the animal intestinal tract, enhance the acid-binding capacity of feed, promote intestinal peristalsis, and thus improve the utilization rate of nutrients. In animal production, GOD can improve animal production performance through such approaches as optimizing the acidic environment of the intestines, inhibiting mycotoxins, and promoting the proliferation of beneficial bacteria. GOD also can alleviate mycotoxin poisoning and ensure feed quality. The article summarizes the physicochemical properties, biological functions, and applications of GOD in animal production, providing reference for further development and application of GOD in animal production.