医学
心力衰竭
射血分数
外科
阻塞性睡眠呼吸暂停
减肥
心功能曲线
心脏病学
肥胖
糖尿病
心肌病
心脏外科
内科学
内分泌学
作者
Tammy L. Kindel,Jennifer L. Strande
标识
DOI:10.1016/j.soard.2017.09.534
摘要
Heart failure due to severe obesity is a complex disease due to multiple mechanisms, including increased body mass, inflammation, and impaired cardiac metabolism that is complicated by obesity-associated co-morbidities, such as type 2 diabetes and obstructive sleep apnea. Bariatric surgery significantly improves cardiac geometry, function, and symptoms related to obesity cardiomyopathy. There is a consistently positive impact of bariatric surgery on diastolic function with the potential to significantly improve systolic function as measured by ejection fraction in patients with advanced heart failure. For end-stage heart failure patients, including those requiring mechanical circulatory support who are ineligible for organ transplant due to morbid obesity, bariatric surgery has been successfully used for weight loss as a bridge to cardiac transplantation.
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