头颈部癌
免疫疗法
头颈部鳞状细胞癌
肿瘤微环境
癌症
医学
生物标志物
癌症研究
癌症免疫疗法
免疫系统
成纤维细胞
免疫学
生物
头颈部
后天抵抗
癌相关成纤维细胞
表型
肿瘤免疫学
临床试验
单克隆抗体
抗体
作者
Aleksandar Obradovic,Diana Graves,Michael Korrer,Yu Wang,Sohini Roy,Abdullah Naveed,Yaomin Xu,Adam Luginbuhl,Joseph Curry,Michael Gibson,Kamran Idrees,Paula Hurley,Peng Jiang,X. Shirley Liu,Ravindra Uppaluri,Charles G. Drake,Andrea Califano,Young J. Kim
标识
DOI:10.1158/1078-0432.ccr-21-3570
摘要
Our findings demonstrate the functional importance of distinct HNCAF subsets in modulating the immunoregulatory milieu of human HNSCC. In addition, we have identified clinically actionable HNCAF subtypes that can be used as a biomarker of response and resistance in future clinical trials.
科研通智能强力驱动
Strongly Powered by AbleSci AI