心力衰竭
内科学
医学
转录组
心脏病学
生物
基因表达
基因
遗传学
作者
Marcella Conning-Rowland,Marilena Giannoudi,Michael Drozd,Oliver Brown,Nadira Yuldasheva,Chew W. Cheng,Paul J. Meakin,Sam Straw,John Gierula,Ramzi Ajjan,Mark T. Kearney,Eylem Levelt,Lee D. Roberts,Kathryn J. Griffin,Richard M. Cubbon
摘要
Diabetes mellitus (DM) increases heart failure incidence and worsens prognosis, but its molecular basis is poorly defined in humans. We aimed to define the diabetic myocardial transcriptome and validate hits in their circulating protein form to define disease mechanisms and biomarkers.
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