芦丁
脂质代谢
溃疡性结肠炎
多酚
化学
阻塞(统计)
新陈代谢
结肠炎
生物化学
医学
抗氧化剂
内科学
统计
数学
疾病
作者
Yi‐Ming Sun,Guixuan Fang,Kangdi Liu,Yulu Zhao,Zhihui Bai,Ting Huang,Honghui Hu,Nan Zhou,Jiali Peng,Lianxiang Luo
出处
期刊:Food & Function
[The Royal Society of Chemistry]
日期:2025-01-01
卷期号:16 (18): 7169-7186
被引量:2
摘要
This study reveals the novel mechanism by which rutin alleviates ulcerative colitis. Rutin targets LCN2, disrupts its interaction axis with ALOX15, inhibits ferroptosis to strengthen intestinal barrier, and reprograms arachidonic acid metabolism.
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