Pitfalls in the Serologic Diagnosis of Maternal Syphilis: A Case Series

Pregnancy is associated with false-positive treponemal and nontreponemal screening test results. We present 5 pregnant women who had reactive treponemal screening and nontreponemal test results but nonreactive Treponema pallidum- particle agglutination test result. Reliance on treponemal screening tests may result in misdiagnosis and unnecessary treatment, unless a specific treponemal test is performed.