极端微生物
灭菌(经济)
发酵
生物生产
生化工程
生物技术
业务
环境科学
生物
细菌
微生物
食品科学
工程类
遗传学
外汇市场
汇率
财务
作者
Jing Zhang,Xu Yan,Helen Park,Nigel S. Scrutton,Tao Chen,Guo‐Qiang Chen
标识
DOI:10.1016/j.copbio.2023.103064
摘要
The use of extremophile organisms such as Halomomas spp. can eliminate the need for fermentation sterilization, significantly reducing process costs. Microbial fermentation is considered a pivotal strategy to reduce reliance on fossil fuel resources; however, sustainable processes continue to incur higher costs than their chemical industry counterparts. Most organisms require equipment sterilization to prevent contamination, a practice that introduces complexity and financial strain. Fermentations involving extremophile organisms can eliminate the sterilization process, relying instead on conditions that are conductive solely to the growth of the desired organism. This review discusses current challenges in pilot- and industrial-scale bioproduction when using the extremophile bacteria Halomomas spp. under nonsterile conditions.
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