大流行
2019年冠状病毒病(COVID-19)
流行病模型
分叉
订单(交换)
2019-20冠状病毒爆发
应用数学
数学
控制理论(社会学)
控制(管理)
医学
病毒学
计算机科学
经济
非线性系统
物理
爆发
人口
内科学
人工智能
环境卫生
疾病
财务
量子力学
传染病(医学专业)
作者
Conghui Xu,Yongguang Yu,Guojian Ren,Xinhui Si
标识
DOI:10.1142/s1793524524500360
摘要
In this paper, a delayed fractional-order epidemic model with general incidence rate and incubation period is proposed for the Corona Virus Disease 2019 (COVID-19) pandemic. The corresponding sufficient conditions are established to analyze the existence and stability of disease-free equilibrium and endemic equilibrium of the proposed model. The conditions for the existence of Hopf bifurcation are obtained by selecting the time delay as the bifurcation parameter. The control strategies for the COVID-19 pandemic are designed, and the corresponding delay fractional order optimal control problem (DFOCP) is analyzed based on the generalized Euler–Lagrange equation. The parameters of the model are identified based on the data of multiple types of the COVID-19 pandemic. Further, the effectiveness of the model in describing the trend of the COVID-19 pandemic is verified. Based on the results of parameter identification, the influence of incubation period on the COVID-19 pandemic is discussed. The forward–backward sweep method (FBSM) is adopted to numerically solve DFOCP, and the control effects under different control measures are analyzed.
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