医学
神经可塑性
慢性疼痛
伤害
神经科学
机制(生物学)
物理医学与康复
物理疗法
精神科
内科学
心理学
认识论
哲学
受体
作者
Steen Petersen-Felix,Michele Curatolo
出处
期刊:Schweizerische Medizinische Wochenschrift
日期:2002-06-01
被引量:29
标识
DOI:10.4414/smw.2002.09913
摘要
The nociceptive system is not just a system for the conduction of pain impulses from the periphery to the brain. We now know that plastic changes can take place in the periphery, the spinal cord and also in higher brain centres following injury or inflammation. These changes may increase the magnitude of the perceived pain and may contribute to the development of chronic pain syndromes. Although our knowledge is growing, we are now almost more confused as to how we should intervene in order to attenuate or inhibit neuroplasticity. The present review examines the current knowledge on mechanism, clinical significance and prevention of neuroplastic changes.
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