Application of fundus fluorescein angiography on retinal diseases in infants

Fundus diseases in infants were difficult to be found in clinic and easily to be misdiagnosed, missed diagnosis and failed to treatment timely, which caused serious damages of vision, even blindness. Fundus fluorescein angiography(FFA) can provide richer diagnostic information for the infants, but in view of the reasons for the equipment and technology, the application was limited. Wide-field digital pediatric retinal imaging system (RetCam Ⅲ), as the representative of the development of the device, progressed in recent years, so that FFA was can be considered to be used in the infants and young children. FFA can record the dynamic state of fluorescein in the blood circulation of infants to observe the development of fundus fluorescein in each phase and to understand the retinal microcirculation or structure in various pathological and physiological changes of fundus. Which has brought great convenience in the diagnosis and treatment of fundus diseases in infants. At present, it is commonly used in the diagnosis and differential diagnosis of retinopathy of prematurity, familial exudative vitreoretinopathy, persistent hyperplastic primary vitreous, Coats disease, retinoblastoma and other diseases.(Int Rev Ophthalmol, 2018, 42: 69-72) Key words: fundus fluorescein angiography; infants