Detection of aberrant crypt foci in the distal colorectum by colonoscopy:a randomized controlled comparison of conventional imaging,narrow band imaging and chromoendoscopy

Aim To compare the detection power of aberrant crypt foci(ACF) by conventional imaging,narrow band imaging,and chromoendoscopy during colonoscopy.Methods Six hundred and seventy outpatients undergoing routine colonoscopy were randomly allocated into three groups:conventional imaging,chromoendoscopy,and narrow band imaging.Detection rate ACF and operation time were compared.Results Total 155 patients with ACF were detected during colonoscopy in 3 groups,the detection rates were 2.19% in conventional imaging group,11.36% in NBI group,and 56.3% in chromoendoscopy group(P 0.01).The operation time was much longer for chromoendoscopy group and NBI group as compared with conventional colonoscopy group.Conclusion Chromoendoscopy and narrow band imaging can improve the detection rate of ACF lesions in the distal colorectum.