Objective:To discuss the effect of health education on the postoperative self-care ability of patients with permanent colostomy due to rectal cancer.Methods:60 patients with rectal cancer after permanent colostomy were randomly divided into intervention group and control group(30 patients for each group).The routine health guidance was given to the patients in the control group and the patients in the intervention group were additionally given health education based on the routine health guidance.The ESCA scale was used to evaluate the patients in both groups respectively on admission and when the patients were discharged from hospital.Results:The ESCA scores increased in both groups when the patients were discharged from hospital and the increasing extent in the intervention group was higher than the control group(P0.05).Conclusion:Health education can effectively improve the self-care ability and quality of life of the patients with permanent colostomy.