Analysis of Male Delayed Gonadal Development in 20 Cases

Objective: To discuss the clinical characteristics and treatment methods of male delayed gonadal development. Methods: Twenty male delayed gonadal development cases were divided into four groups including hypergonadotropic hypogonadism group, idiopathic hypogonadotropic hypogonadism (IHH) group, acquired hypogonadotropic hypogonadism (AHH) group and constitutional delayed puberty group, and were analyzed respectively. Results: The abnormality of hypergonadotropic hypogonadism usually combined with autosomal abnormality and mental retardation. No obvious reasons for hypogonadism and serum gonadotropin decreased in IHH, and systemic treatment was needed. Patients with AHH had pituitary or intracranial lesion or other systemic disease that could cause hypogonadism. Constitutional delayed puberty had no obvious reasons, special treatment was not needed, and idiopathetic gonadol development might appear finally. Conclusion: Four types of male delayed gonadal development should be distinguished and given different treatment in clinic.