Clinical observation on the effect of three laxatives such as Senna in the treatment of bedridden patients with constipation

Objective To study the effect of Senna,Phenolphthalein combined with Cisapride and Glycerine Enema in the treatment of bedridden patients with constipation.Methods According to the sequential method,selected cases were divided into Senna group(60 cases),Phenolphthalein combined with Cisapride group(60 cases) and Glycerine Enema group(60 cases).Stool discharge rate within 12 hours after treatment,first defecation time,defecation frequency,character and weight of stool,blood pressure when defecating,adverse reactions such as hemoproctia,patient acceptance level of all patients in three groups were observed.Results Stool discharge rate within 12 hours after treatment,first defecation time,defecation frequency,character and weight of stool and patient acceptance level of three groups patients showed statistically significant difference(P 0.01,P 0.05).While blood pressure when defecating,adverse reactions such as hemoproctia of three groups patients were not statistically significant(P 0.05).Conclusion The three kinds of laxatives are safe and effective to relieve constipation of bedridden patients,and there are advantages and disadvantages to each laxative.The effect of senna immersion fluid taken orally and glycerine enema clystered is better than phenolphthalein combined with cisapride.