To evaluate the clinical significance and characteristics of intrauterine hematomas detected by ultrasonography in the first trimester of pregnancy. A retrospective study was designed to compare the obstetrical outcome in 33 pregnant women with intrauterine hematoma who spontaneously aborted, to 153 controls who delivered after the hematoma was diagnosed. Statistical analysis was made by Student's t-test. Multiparity and vaginal infections were significantly greater in the abortion group. There was no significant difference with regard to maternal age, gestational diabetes, termination of pregnancy and previous loss. Retroplacental or subchorionic position of the hematoma was not significantly correlated with an increased risk for abortion. The cervical (P = 0.003) and posterior location (P = 0.001) of the hematoma significantly influenced the risk of abortion. The volume of the hematoma was significantly greater in the abortion group (P = 0.02). The abortion rate was also significantly greater in those who were spotting, bleeding or pelvic pain (P = 0.02). In our series the presence and the characteristics of an intrauterine hematoma detected by ultrasonography during the first trimester of pregnancy may identify the pregnant women at increased risk for spontaneous abortion.