Lewis Acid-Lewis Base Bifunctional Schiff Base-Titanium, Vanadium Catalysis for Enantioselective Cyanosilylation of Benzaldehyde and Oxidation of Sulfides to Chiral Sulfoxides

New bifunctional asymmetric catalysts containing a Lewis acid Ti(IV)/V(IV) and a Lewis base were developed and applied to the catalytic asymmetric cyanosilylation of benzaldehyde and oxida- tion of sulfides to chiral sulfoxides. The products were obtained with moderate to low enantiomeric excess.