Electrophilic Aminating Agents in Total Synthesis

Abstract Classical amination methods involve the reaction of a nitrogen nucleophile with an electrophilic carbon center; however, in recent years, umpoled strategies have gained traction where the nitrogen source acts as an electrophile. A wide range of electrophilic aminating agents are now available, and these underpin a range of powerful C−N bond‐forming processes. In this Review, we highlight the strategic use of electrophilic aminating agents in total synthesis.