自愈水凝胶
生物相容性
肿胀 的
木质素
膨胀能力
化学
化学工程
牛皮纸
材料科学
高分子化学
有机化学
复合材料
工程类
作者
Lenka Musilová,Aleš Mráček,Adriána Kovalcik,Petr Smolka,Antonín Minařík,Petr Humpolíček,Robert Vícha,Petr Ponížil
标识
DOI:10.1016/j.carbpol.2017.10.048
摘要
Effects of the addition of water soluble glycinated Kraft lignin (WS/KL) on the mechanical stability and biocompatibility of hyaluronan (NaHy) hydrogels were evaluated in this work. Water soluble lignin was obtained by the modification of Kraft lignin via a Mannich reaction. It was found that WS/KL is highly compatible with hyaluronan due to its improved water solubility, which favours its use in designing new advanced composite hydrogels. The effects of the concentration of WS/KL on morphological, swelling and creep/recovery behaviours of hyaluronan hydrogels were investigated. It was detected that the creep resistance and creep recovery of NaHy hydrogels was improved by the incorporation of up to 3% (w/w) of WS/KL. In contrast, the swelling capacity of hydrogels was decreased. The cytotoxicity tests proved that glycinated KL lignin limits the viability of cells only slightly, and the final hyaluronan/lignin hydrogels were non-toxic materials.
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