曲妥珠单抗
曲妥珠单抗
帕妥珠单抗
医学
化疗
内科学
肿瘤科
抗体-药物偶联物
药品
药理学
抗体
入射（几何）
心脏毒性
乳腺癌
临床试验
结合
癌症
不利影响
化疗方案
紫杉烷
作者
Seth, Lakshya,Bhave, Aditya,Kollapaneni, Sai,Shah, Viraj,Nahle, Tarek,Blaes, Anne,Dent, Susan,Hurvitz, Sara A.,Guha, Avirup
出处
期刊：PubMed
[National Institutes of Health]
日期：2025-11-03
卷期号：8 (11): e2540336-e2540336
标识
DOI：10.1001/jamanetworkopen.2025.40336
摘要
This meta-analysis found that trastuzumab emtansine was associated with the lowest incidence of LVEF decrease, and trastuzumab deruxtecan, trastuzumab plus chemotherapy, and trastuzumab plus pertuzumab plus chemotherapy had similar incidences. More research is needed into the cardiotoxic effects of these therapies.
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(2025-6-4)
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