Visible-light-induced nickel-catalysed cross-coupling of 2,2,2-trifluoroethyl pinacol borate with heteroaryl bromides

We report a photo-nickel co-catalysed strategy to access a variety of trifluoroethyl heteroarenes. The synthetic value of this protocol was proved by its scalability in flow and application to the late-stage functionalization of drug-like molecules.