医学
结直肠癌
切除术
肿瘤科
全身疗法
危险分层
临床实习
外科切除术
内科学
外科
普通外科
癌症
临床试验
淋巴
总体生存率
结肠疾病
梅德林
治疗
出处
期刊:PubMed
[National Institutes of Health]
日期:2026-05-25
卷期号:29 (5): 627-635
标识
DOI:10.3760/cma.j.cn441530-20260313-00118
摘要
Curative resection following conversion therapy has become a key strategy for improving the prognosis of patients with advanced colorectal cancer (CRC). Based on the latest evidence from clinical studies, international clinical practice guidelines, and multicenter investigations, this review systematically summarizes surgical strategies after conversion therapy for CRC with metastases to the liver, lung, peritoneum, and retroperitoneal lymph nodes. Particular emphasis is placed on resectability assessment systems, biological stratification of tumor behavior, optimal timing of surgery, and principles of optimizing surgical strategies. By integrating function-preserving surgery, local and regional therapies, a precision surgery framework centered on achieving R0 resection is established.
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