Ivabradine for treatment of tachyarrhythmias in children and young adults

Key Teaching Points•Ivabradine is a novel heart rate–reducing agent that acts via selective inhibition of the pacemaker current.•Ivabradine demonstrates use dependence, resulting in a greater effect at higher heart rates.•Ivabradine has a hemodynamically neutral profile, in contrast to many alternative antiarrhythmic agents.•Ivabradine shows promise as an effective treatment for automatic tachyarrhythmias in pediatric and congenital heart disease patients. •Ivabradine is a novel heart rate–reducing agent that acts via selective inhibition of the pacemaker current.•Ivabradine demonstrates use dependence, resulting in a greater effect at higher heart rates.•Ivabradine has a hemodynamically neutral profile, in contrast to many alternative antiarrhythmic agents.•Ivabradine shows promise as an effective treatment for automatic tachyarrhythmias in pediatric and congenital heart disease patients.